GEM 21S® Growth Factor Enhanced Matrix

GEM 21S® is a synthetic bone graft composed of purified, sterile recombinant (bioengineered) platelet-derived growth factor (rhPDGF) and β-TCP. PDGF is naturally found in the body (present in the platelets in your blood) and is often referred to as nature’s wound healing protein. GEM 21S® increases the amount of PDGF at the grafted site to aid in faster, more bone and better healing.1
Key Benefits:
- Completely synthetic growth factor-enhanced matrix with rhPDGF-BB and β-TCP.
- Promotes regeneration of bone, periodontal tissues, and peri-implant structures.
- Facilitates angiogenesis and osteogenesis, mimicking the body's natural healing processes.
References:
- GEM 21S® Instructions for Use.
- Wang HL, et al.: J Periodontol. 1994 May; 65 (5): 429-36.
- Graves DT. Ann Periodontol. 1997; 2: 259-267.
- Piche JE, et al.: Bone. 1989; 10(2): 131-189.
- Based on in-vitro and in-vivo data.
- Lynch SE, Introduction: Tissue Engineering, Applications in Maxillofacial Surgery and Periodontics. Lynch SE, Genco RJ and Marx RE Eds. Quintessence Publishing Co. 1999.
- Nevins M. et al.: J Periodontol. 2003 Sep; 74(9):1282-92.
- McGuire M, et al.: Int J Periodontics Restorative Dent. 2009; 29:7-21.
Optimising Soft Tissue & Bone Healing for Teeth & Implants by Dr Michael McGuire & Dr. Todd Scheyer


The Science
How Dr. Sam Lynch Revolutionised Oral Surgery With GEM 21S® & Growth Factors
