Geistlich Mucograft®
User Benefits
Geistlich Mucograft® is a 3D collagen matrix designed specifically for soft tissue regeneration in the oral cavity1. It is indicated for gaining keratinised tissue2,3,4 and for recession coverage5,6.
Geistlich Mucograft® provides an alternative to autologous soft tissue grafts2,4,5,6. Painful harvesting of tissue is avoided, benefiting patients and clinicians alike.
Leading clinicians rely on Geistlich Mucograft®:
- No harvest-site morbidity2,3,5-7
- Less pain compared with autologous grafts2,4
- Reduced surgical chair-time compared with autologous grafts2-6
- Natural soft tissue colour and texture match5,8,9
- Early vascularisation and good soft tissue ingrowth10,11
- Good wound healing, also in open situations2
- Easy handling2 and application in a dry state
Geistlich Mucograft® consists of two structures: the compact structure provides stability while allowing open healing; the spongy structure supports blood clot stabilisation and ingrowth of soft tissue cells.
References:
- Biocompatibility according to ISO 10993-1. Data on file, Geistlich Pharma AG, Wolhusen, Switzerland
- Sanz M, et al.: J Clin Periodontol 2009; 36(10): 868-76. (clinical study)
- Konter U, et al.: Deutsche Zahnärztliche Zeitschrift 2010; 65: 723-30. (clinical study)
- Lorenzo R, et al.: Clin Oral Impl Res 2012; 23(3): 316-24. (clinical study)
- McGuire MK & Scheyer ET: J Periodontol 2010; 81(8): 1108-17. (clinical study)
- Cardaropoli D, et al.: J Periodontol 2012; 83(3): 321-28. (clinical study)
- Herford AS, et al.: J Oral Maxillofac Surg 2010; 68(7): 1463-70. (clinical study)
- Thoma, D, et al.: J Clin Periodontol 2012; 39(2): 157-65. (clinical study)
- Nevins M, et al.: Int J Periodontics Restorative Dent 2011; 31(4): 367-73. (clinical study)
- Ghanaati S, et al.: Biomed Mater. 2011 Feb; 6(1): 015010. (pre-clinical study)
- Rocchietta I, et al.: Int J Periodontics Restorative Dent. 2012; 32(1): e34-40. (pre-clinical study)
* Mucograft® (prototype) exhibited highly similar physical, mechanical and biological properties to the final product Geistlich Mucograft® differing only in the porcine collagen source used.
Application
Geistlich Mucograft® is easy to handle compared with autologous soft tissue grafts1:
- Unlimited availability and consistent quality
- No need for pre-treatment or pre-hydration
- Measure the defect and trim the matrix to the required shape
- Apply the dry Geistlich Mucograft® to the defect; it will moisten rapidly due to marked hydrophilicity
- Position the compact structure facing outwards and the spongy structure towards the bone or periosteum
- Soaked matrix adapts spontaneously to contours and adheres well to defect
- The compact structure provides optimal suture pull-out strength
References:
- Sanz M, et al.: J Clin Periodontol 2009; 36(10): 868-76. (clinical study)
- Abundo R & Corrente G: Chirurgia plastica parodontale – Trattamento estetico delle recessioni gengivali. ACME Edizioni, 2010. (book, clinical)
Product Range
Geistlich Mucograft® consists of porcine collagen and is specifically designed for soft tissue regeneration. The matrix is available in three sizes:
- 15x20mm
- 20x30mm