Peri-Implantitis
Scientific background
Peri-implant infections are pathological conditions surrounding dental implants. Mucositis refers to inflammation and ulceration in the soft tissues around an implant and is a reversible host response to periodontal pathogens. Peri-Implantitis, the destructive inflammatory process affecting both soft and hard tissue surrounding a dental implant, is more severe and leads to bone loss1.
The typical signs and symptoms of the diseases, as discussed in various consensus conferences, can be described as follows2-8:
Mucositis
- Bleeding on probing
- Redness and swelling of soft tissue
- No loss of supporting bone
Peri-implantitis
- Crater-like bone defect
- Bleeding and/or suppuration on probing
- No implant mobility
- >4mm peri-implant probing depth
A reliable diagnosis of peri-implantitis requires the simultaneous presence of all above listed signs and symptoms. A single feature alone is not sufficient for the diagnosis.
Treatment of peri-implantitis
Peri-implantitis should be treated systematically. Bacterial plaque removal with surgical and/or non-surgical therapy is essential to prevent further progression and prepare the defect for regenerative procedures9.
Guided bone regeneration with Geistlich Bio-Oss® and Geistlich Bio-Gide® regenerates the osseous defect after implant surface decontamination10.
References:
- Lang NP, et al.: Ann Periodontol 1997; 2(1): 343-56 (Clinical study)
- Mombelli A, et al., Clin Oral Implants Res 2012; 23 Suppl 6: 67-76 (Systematic review)
- Lang NP, et al., J Clin Periodontol 2011; 38 Suppl 11: 178-81 (Systematic review)
- Lindhe J, et al., J Clin Periodontol 2008; 35(8 Suppl): 282-85 (Clinical study)
- Mombelli A, Criteria for success. Monitoring In: Proceedings of the first European Workshop on Periodontology, (eds.) N.P. Lang & T. Karring, pp. 317–325. London: Quintessence 1994 (Book chapter)
- Mombelli A, Prevention and therapy of peri-implant infections. In: Proceedings of the 3rd European Workshop on Periodontology, (eds.) N.P. Lang, T. Karring & J. Lindhe, pp. 281–303. Berlin: Quintessenz Verlag 1999 (Book chapter)
- Tomasi DP & Derks J, J Clin Periodontol 2012; 39 Suppl 12: 207-23 (Systematic review)
- Zitzmann NU & Berglundh T, J Clin Periodontol 2008; 35(8 Suppl): 286-91 (Systematic review)
- Schwarz F & Becker J, Peri-implant Infection: Etiology, Diagnosis and Treatment. Quintessence Publishing 2007 (Book)
- Schwarz F, et al., J Clin Periodontol 2009; 36(9): 807-14 (Clinical study)
Regenerative treatment of peri-implantitis
A systematic review of regenerative measures following anti-infection treatment revealed that peri-implantitis lesions can be effectively filled with bone substitute materials1. Geistlich Bio-Oss® provides more radiographic bone fill in peri-implant lesions compared with autogenous bone2.
When defect fill of peri-implantitis defects is required, use of Geistlich Bio-Oss® in combination with a Geistlich Bio-Gide® membrane results in marked clinical improvement3.
References:
- Renvert S, et al., Clin Oral Implants Res 2012; 23 Suppl 6: 84-94 (Clincal study)
- Aghazadeh A, et al., J Clin Periodontol 2012; 39(7): 666-73 (Clinical study)
- Schwarz F, et al., J Clin Periodontol 2009; 36(9): 807-14 (Clinical study)
Regenerative treatment of peri-implantitis
Clinical Case
Surgical regenerative treatment of a peri-implant bone defect with a favourable long-term result.
Defects caused by peri-implantitis can be corrected with Geistlich Bio-Oss® bone replacement material in combination with a Geistlich Bio-Gide® membrane.
References:
- Renvert S, et al., Clin Oral Implants Res 2012; 23 Suppl 6: 84-94 (Clincal study)
- Aghazadeh A, et al., J Clin Periodontol 2012; 39(7): 666-73 (Clinical study)
- Schwarz F, et al., J Clin Periodontol 2009; 36(9): 807-14 (Clinical study)
Perio-System Combi-Pack combines the improved handling attributes of Geistlich Bio-Oss® Collagen 100mg and Geistlich Bio-Gide® Perio 16 x 22mm. Used together, they offer optimal properties for regenerative periodontal procedures.
Product efficacy demonstrated in about 1,400 scientific publications
Decades of experience with biomaterials and pioneering work achieved are documented in meaningful scientific evidence. The efficacy of Geistlich’s biomaterials is documented in about 1,400 scientific publications – when it comes to the safety and quality of its products, Geistlich doesn’t compromise. To learn from the best and gain valuable expertise, the company networks with renowned international experts, university partners and esteemed clinical practitioners. New treatment concepts and products are born from the exchanges between this network of expertise. Geistlich places great importance on training medical professionals. The strive for excellence means that a Geistlich biomaterial is used every 15 seconds around the world.